Important Service Update

The main symptom of acanthosis nigricans is patches of skin that are darker and thicker than usual.

They can appear anywhere on the body.

The patches often appear gradually without any other symptoms.

Sometimes the skin may be itchy.

See a GP if:

A GP can usually tell if it's acanthosis nigricans by looking at your skin.

Although acanthosis nigricans is usually harmless, it's best to get any skin changes checked out.

Rarely, it can be a sign of something more serious, such as cancer.

You may need some tests to find out what's causing the patches.

The most common cause of acanthosis nigricans is obesity.

Other causes include:

• type 2 diabetes
• conditions that affect hormone levels – such as Cushing's syndrome, polycystic ovary syndrome or an underactive thyroid
• taking certain medicines – including steroids or hormone treatments like the contraceptive pill
• rarely, cancer – usually stomach cancer
• rarely, a faulty gene inherited from your parents

Sometimes healthy people with no other conditions get acanthosis nigricans. This is more common in people with black or brown skin.

Once a GP knows what's causing acanthosis nigricans, they can recommend the best treatment.

The patches should fade over time once the cause is treated.

If you're very overweight, a GP may recommend losing weight.

Depending on the cause, they may also recommend:

• medicine to balance your hormones
• medicine to balance your insulin levels
• changing your medicine to one that does not cause the patches

There's no specific treatment for the patches themselves. A skin specialist (dermatologist) may be able to suggest treatments to improve their appearance, but finding and treating the cause is usually recommended first.